| 29/03/08 | Columbus Adam Moffat (26'), Alejandro Moreno (76') |
2 : 0 | Toronto FC |
| 29/03/08 | Real Salt Lake | 1 : 1 | Chicago (71') Bakary Soumare,(92') Cuauhtemoc Blanco |
| 29/03/08 | Kansas City Ivan Trujillo (47'), Claudio Lopez (61') |
2 : 0 | D.C. United |
| 29/03/08 | Colorado Terry Cooke (10'),Christian Gomez (60'), Omar Cummings (67') ,Colin Clark (80') |
4 : 0 | Los Angeles |
| 29/03/08 | New England Steve Ralston (16'),Adam Cristman (32') , Sainey Nyassi (93') |
3 : 0 | Houston |
| 30/03/08 | FC Dallas Juan Toja (21') |
1 : 1 | CD Chivas USA (84') Maykel Galindo |
