| Litex | Hamburg | 0 - 1 | 1 - 3 |
| Lens | København (aet) | 1 - 1 | 1 - 2 |
| Artmedia | Panathinaikos | 1 - 2 | 0 - 3 |
| Sparta (4-3p) | OB | 0 - 0 | 0 - 0 |
| Empoli | Zürich | 2 - 1 | 0 - 3 |
| Sochaux | Panionios | 0 - 2 | 1 - 0 |
| Anderlecht | Rapid Wien | 1 - 1 | 1 - 0 |
| Paços de Ferreira | AZ | 0 - 1 | 0 - 0 |
| Zenit | Standard | 3 - 0 | 1 - 1 |
| Leverkusen | Leiria | 3 - 1 | 2 - 3 |
| Villarreal | BATE | 4 - 1 | 2 - 0 |
| Sion | Galatasaray | 3 - 2 | 1 - 5 |
| Atlético | Erciyesspor | 4 - 0 | 5 - 0 |
| Tampere | Bordeaux | 2 - 3 | 1 - 1 |
| Getafe (ag) | Twente | 1 - 0 | 2 - 3 |
| Groclin | Crvena Zvezda | 0 - 1 | 0 - 1 |
| Midtjylland | Lokomotiv Moskva | 1 - 3 | 0 - 2 |
| Groningen | Fiorentina (3-4p) | 1 - 1 | 1 - 1 |
| Rabotnicki | Bolton | 1 - 1 | 0 - 1 |
| AEK | Salzburg | 3 - 0 | 0 - 1 |
| Nürnberg (ag) | Rapid Bucureşti | 0 - 0 | 2 - 2 |
| Everton | Metalist | 1 - 1 | 3 - 2 |
| Tottenham | Anorthosis | 6 - 1 | 1 - 1 |
| Sarajevo | Basel | 1 - 2 | 0 - 6 |
| Austria Wien | Vålerenga | 2 - 0 | 2 - 2 |
| H. Tel-Aviv | AIK | 0 - 0 | 1 - 0 |
| Aris (ag) | Zaragoza | 1 - 0 | 1 - 2 |
| Dinamo Bucuresti | Elfsborg (ag) | 1 - 2 | 1 - 0 |
| Loko Sofia | Rennes | 1 - 3 | 2 - 1 |
| Brann (ag) | Club Brugge | 0 - 1 | 2 - 1 |
| Bayern | Belenenses | 1 - 0 | 2 - 0 |
| Aberdeen (ag) | Dnipro | 0 - 0 | 1 - 1 |
| Heerenveen | Helsingborg | 5 - 3 | 1 - 5 |
| Toulouse (ag) | CSKA Sofia | 0 - 0 | 1 - 1 |
| Sampdoria | AaB (ag) | 2 - 2 | 0 - 0 |
| Spartak Moskva | Häcken | 5 - 0 | 3 - 1 |
| Hammarby | Braga | 2 - 1 | 0 - 4 |
| Larissa | Blackburn | 2 - 0 | 1 - 2 |
| Mladá Boleslav (4-2p) | Palermo | 0 - 1 | 1 - 0 |
| Dinamo Zagreb (ag) | Ajax | 0 - 1 | 3 - 2 |
