| 01/11/07 | Valladolid Llorente 16 | 1-1 | Barcelona Ronaldinho 41 |
| 01/11/07 | Espanyol | 0-0 | Murcia |
| 03/11/07 | Mallorca | 0-2 | Valencia Morientes 45, 61 |
| 03/11/07 | Sevilla Keita 18, Luis Fabiano 20 | 2-0 | Real Madrid |
| 04/11/07 | Atlético Pablo 9, Simao 24, Aguero 61 | 3-4 | Villarreal Rossi 30, Fuentes 40, Nihat 68, 89 |
| 04/11/07 | Levante Rigano 1, 15, 33 | 3-0 | Almería |
| 04/11/07 | Zaragoza Oliveira 13, Diego Milito 89 | 2-3 | Valladolid Victor 27, 30, Alvaro Rubio 32 |
| 04/11/07 | Osasuna | 0-2 | Getafe Pablo 80(p), Granero 81 |
| 04/11/07 | Racing Tchite 55 | 1-1 | Espanyol Tamudo 90(p) |
| 04/11/07 | Murcia | 0-2 | Deportivo Xisco 55, Guardado 72 |
| 04/11/07 | Barcelona Henry 32, Ronaldinho 52, 90 | 3-0 | Betis |
| 04/11/07 | Athletic Etxeberria 51, 61 | 2-0 | Recreativo |
| 10/11/07 | Getafe Manu 28, Albin 90 | 2-0 | Barcelona |
| 10/11/07 | Valencia Helguera 13, Villa 26, 50 | 3-0 | Murcia |
| 11/11/07 | Almería | 0-0 | Atlético |
| 11/11/07 | Espanyol Tamudo 39, Aitor Ocio 90(o) | 2-1 | Athletic Gabilondo 2 |
| 11/11/07 | Valladolid Sesma 64 | 1-0 | Levante |
| 11/11/07 | Betis Xisco 82, Pavone 90 | 2-1 | Zaragoza D'Alessandro 35 |
| 11/11/07 | Recreativo Carlos Martins 71 | 1-0 | Osasuna |
| 11/11/07 | Deportivo | 0-1 | Racing Tchite 69 |
| 11/11/07 | Real Madrid Robinho 12, 17, Raul 63, van Nistelrooy 73 | 4-3 | Mallorca Varela 14, 37, Guiza 59 |
| 11/11/07 | Villarreal Franco 31, 68, Fernandez 87(p) | 3-2 | Sevilla Kanoute 34, Luis Fabiano 50 |
| 24/11/07 | Barcelona Milito 64, Bojan 66, Messi 82(p) | 3-0 | Recreativo |
| 24/11/07 | Sevilla Kanoute 50 | 1-2 | Mallorca Ibagaza 17, Varela 38 |
| 24/11/07 | Murcia De Lucas 49 | 1-1 | Real Madrid Robinho 9 |
| 25/11/07 | Osasuna Portillo 75 | 1-2 | Espanyol Angel 30, Valdo 33 |
| 25/11/07 | Athletic Barragan 22(o), David Lopez 54 | 2-2 | Deportivo Riki 63, Taborda 90 |
| 25/11/07 | Villarreal Nihat 13 | 1-1 | Almería Negredo 53 |
| 25/11/07 | Atlético Maniche 3, Maxi 50, 56, Pedro Lopez 90(o) | 4-3 | Valladolid Victor 39, Sisi 47, Llorente 54 |
| 25/11/07 | Levante Tommasi 39, Riga 41, 50, Javi Fuego 81 | 4-3 | Betis Arzu 9, Edu 25(p), Pavone 52 |
| 25/11/07 | Racing Jorge Lopez 70 | 1-0 | Valencia |
| 25/11/07 | Zaragoza D'Alessandro 81 | 1-1 | Getafe Sousa 65 |
