| 01/03/08 | Atlético Aguero 36, 71, Maxi 43, Forlan 62(p) | 4-2 | Barcelona Ronaldinho 30, Eto'o 74 |
| 01/03/08 | Recreativo Caceres 17, Carlos Martins 90 | 2-3 | Real Madrid Raul 28, Robinho 74, 90 |
| 01/03/08 | Deportivo Wilhelmsson 35(p), Lafita 65 | 2-1 | Sevilla Kanoute 25 |
| 01/03/08 | Espanyol Luis Garcia 4, 51(p) | 2-0 | Valencia |
| 02/03/08 | Valladolid | 0-1 | Racing Duscher 86 |
| 02/03/08 | Betis Arzo 16(o), Edu 42, Pavone 57, Rafael Sobis 75(p) | 4-0 | Murcia |
| 02/03/08 | Getafe Mario Cotelo 2, Albin 11, Ramis 59(o) | 3-3 | Mallorca Guiza 14, Arango 77, Ramis 80 |
| 02/03/08 | Levante Geijo 21, Riga 61 | 2-1 | Zaragoza Oscar 66 |
| 02/03/08 | Villarreal | 0-0 | Osasuna |
| 02/03/08 | Almería Negredo 60(p) | 1-1 | Athletic Llorente 73 |
| 08/03/08 | Real Madrid Higuain 43, Raul 73(p) | 2-1 | Espanyol Valdo 30 |
| 08/03/08 | Zaragoza Pablo 36(o), Diego Milito 73(p) | 2-1 | Atlético Simao 26 |
| 09/03/08 | Sevilla Keita 28, Luis Fabiano 49 | 2-1 | Levante Riga 5 |
| 09/03/08 | Osasuna Kike Sola 6, Cruchaga 29 | 2-1 | Almería Corona 20 |
| 09/03/08 | Athletic Gabilondo 7, 68 | 2-0 | Valladolid |
| 09/03/08 | Racing Duscher 51, Garay 59, Tchite 88 | 3-0 | Betis |
| 09/03/08 | Murcia | 0-3 | Getafe Pablo 56, Albin 84, Casquero 87 |
| 09/03/08 | Mallorca Guiza 22, 32, Arango 21, 48, 50, Borja Valero 38, 41 | 7-1 | Recreativo Ruben 40 |
| 09/03/08 | Valencia Mata 17, Villa 24 | 2-2 | Deportivo Sergio 37, Lafita 45 |
| 09/03/08 | Barcelona Xavi 67 | 1-2 | Villarreal Senna 32(p), Tomasson 81 |
| 15/03/08 | Recreativo Sinama Pongolle 19, 70, Ruben 59, Marquitos 85 | 4-2 | Murcia De Lucas 16, Ivan Alonso 74(p) |
| 15/03/08 | Deportivo Pepe 58(o) | 1-0 | Real Madrid |
| 15/03/08 | Betis Gonzalez 38 | 1-2 | Athletic Yeste 9, David Lopez 66(p) |
| 15/03/08 | Valencia Albiol 90 | 1-2 | Sevilla Luis Fabiano 12, 22 |
| 16/03/08 | Espanyol Luis Garcia 58(p), 88 | 2-1 | Mallorca Guiza 13 |
| 16/03/08 | Villarreal Nihat 11, Rossi 66(p) | 2-0 | Zaragoza |
| 16/03/08 | Valladolid | 0-0 | Osasuna |
| 16/03/08 | Getafe Gavilan 67, 77 | 2-1 | Racing Smolarek 54 |
| 16/03/08 | Almería Pulido 33, Uche 86 | 2-2 | Barcelona Bojan 17, Eto'o 57 |
| 16/03/08 | Atlético Simao 24, Forlan 39, 52 | 3-0 | Levante |
| 22/03/08 | Mallorca Arango 23 | 1-0 | Deportivo |
| 22/03/08 | Sevilla Diego Capel 48 | 1-2 | Atlético Maxi 19, Aguero 57 |
| 23/03/08 | Levante Miguel Angel 65 | 1-2 | Villarreal Fernandez 28, Franco 83 |
| 23/03/08 | Zaragoza Oliveira 68 | 1-1 | Almería Negredo 89 |
| 23/03/08 | Barcelona Eto'o 24, Iniesta 47, Bojan 62, 84 | 4-1 | Valladolid Sesma 31(p) |
| 23/03/08 | Osasuna | 0-1 | Betis Gonzalez 54 |
| 23/03/08 | Racing Orteman 81, Smolarek 90 | 2-0 | Recreativo |
| 23/03/08 | Murcia Ivan Alonso 36(p), 47, Abel 63(p), Richi 85 | 4-0 | Espanyol |
| 23/03/08 | Real Madrid Raul 35, 56 | 2-3 | Valencia Villa 34, 67(p), Arizmendi 89 |
| 23/03/08 | Athletic Etxeberria 29 | 1-0 | Getafe |
| 29/03/08 | Betis Edu 64, 78, Juanito 76 | 3-2 | Barcelona Bojan 14, Eto'o 15 |
| 29/03/08 | Villarreal Santi Cazorla 39, Nihat 43, 66 | 3-0 | Atlético |
| 30/03/08 | Recreativo Amorebieta 15(o) | 1-1 | Athletic Aduriz 82 |
| 30/03/08 | Espanyol | 0-3 | Racing Oscar Serrano 16, Munitis 26, Bolado 90 |
| 30/03/08 | Getafe | 0-2 | Osasuna Miguel Flano 41, Punal 69(p) |
| 30/03/08 | Valladolid Victor 51(p), Llorente 74 | 2-1 | Zaragoza Zapater 29 |
| 30/03/08 | Almería Soriano 2, Felipe Melo 36 | 2-1 | Levante Iborra 90 |
| 30/03/08 | Valencia | 0-3 | Mallorca Guiza 11, 55, Ramis 20 |
| 30/03/08 | Deportivo Xisco 23, 46, 49 | 3-1 | Murcia De Lucas 4 |
| 30/03/08 | Real Madrid Heinze 8, Raul 39, Higuain 64 | 3-1 | Sevilla Kanoute 38 |
