| 25/08/07 | Real Madrid Raul 14, Sneijder 79 | 2-1 | Atlético Aguero 0 |
| 25/08/07 | Sevilla Jesus Navas 45, Luis Fabiano 66, Kanoute 69, Kerzhakov 81 | 4-1 | Getafe Pablo 1 |
| 25/08/07 | Murcia Mejia 18, Baiano 69 | 2-1 | Zaragoza Oliveira 31 |
| 26/08/07 | Deportivo | 0-3 | UD Almeria Negredo 18, Soriano 34, Crusat 50 |
| 26/08/07 | Athletic | 0-0 | Osasuna |
| 26/08/07 | Racing | 0-0 | Barcelona |
| 26/08/07 | Mallorca Ibagaza 24(p), 71, Guiza 56 | 3-0 | Levante |
| 26/08/07 | Recreativo Sinama Pongolle 26 | 1-1 | Betis Nano 40 |
| 26/08/07 | Valencia | 0-3 | Villarreal Tomasson 15, Rossi 62(p), Santi Cazorla 72 |
| 26/08/07 | Espanyol | 0-1 | Valladolid Llorente 54 |
