| 01/03/08 | Arsenal Bendtner 90 | 1-1 | Aston Villa Senderos 27(o) |
| 01/03/08 | Birmingham Forssell 7, 59, 81, Larsson 55 | 4-1 | Tottenham Jenas 90 |
| 01/03/08 | Derby | 0-0 | Sunderland |
| 01/03/08 | Fulham | 0-3 | Man. United Hargreaves 15, Park 44, Davies 72(o) |
| 01/03/08 | Middlesbrough | 0-1 | Reading Harper 90 |
| 01/03/08 | Newcastle | 0-1 | Blackburn Derbyshire 90 |
| 01/03/08 | West Ham | 0-4 | Chelsea Lampard 17(p), Cole 20, 64, Ballack 22 |
| 01/03/08 | Man. City | 0-0 | Wigan |
| 02/03/08 | Bolton Cohen 79 | 1-3 | Liverpool Jaaskelainen 12(o), Babel 60, Aurelio 75 |
| 02/03/08 | Everton Yakubu 1, 81, Cahill 73 | 3-1 | Portsmouth Defoe 38 |
| 05/03/08 | Liverpool Torres 8, 61, 81, Gerrard 83 | 4-0 | West Ham |
| 08/03/08 | Blackburn Pedersen 59 | 1-1 | Fulham Bullard 89 |
| 08/03/08 | Liverpool Pennant 43, Torres 45, Gerrard 51 | 3-0 | Newcastle |
| 08/03/08 | Reading Long 62, Kitson 88 | 2-0 | Man. City |
| 09/03/08 | Sunderland | 0-1 | Everton Johnson 55 |
| 09/03/08 | Tottenham Berbatov 8, 11, Gilberto 85, Bent 90 | 4-0 | West Ham |
| 09/03/08 | Wigan | 0-0 | Arsenal |
| 12/03/08 | Aston Villa Barry 74(p) | 1-1 | Middlesbrough Downing 23 |
| 12/03/08 | Portsmouth Defoe 6(p), 9, Hreidarsson 49, Kanu 90 | 4-2 | Birmingham Muamba 10, Larsson 40 |
| 12/03/08 | Chelsea Lampard 28(p), 57, 66, 72, Kalou 42, Cole 64 | 6-1 | Derby Jones 73 |
| 15/03/08 | Derby | 0-1 | Man. United Ronaldo 76 |
| 15/03/08 | Liverpool Mascherano 19, Torres 48 | 2-1 | Reading Matejovsky 5 |
| 15/03/08 | Portsmouth Defoe 11, Reo-Coker 38(o) | 2-0 | Aston Villa |
| 15/03/08 | Sunderland | 0-1 | Chelsea Terry 10 |
| 15/03/08 | West Ham Ashton 39, Sears 81 | 2-1 | Blackburn Santa Cruz 19 |
| 15/03/08 | Arsenal Toure 86 | 1-1 | Middlesbrough Aliadiere 25 |
| 16/03/08 | Fulham McBride 67 | 1-0 | Everton |
| 16/03/08 | Wigan Heskey 34 | 1-0 | Bolton |
| 16/03/08 | Man. City Ireland 59, Onuoha 72 | 2-1 | Tottenham Keane 32 |
| 17/03/08 | Birmingham McFadden 33 | 1-1 | Newcastle Owen 56 |
| 19/03/08 | Man. United Ronaldo 9, 19 | 2-0 | Bolton |
| 19/03/08 | Tottenham Woodgate 12, Berbatov 61, Huddlestone 75, Keane 88 | 4-4 | Chelsea Drogba 3, Essien 20, Cole 52, 80 |
| 22/03/08 | Tottenham Bent 80, O'Hara 82 | 2-0 | Portsmouth |
| 22/03/08 | Aston Villa | 0-1 | Sunderland Chopra 83 |
| 22/03/08 | Blackburn Santa Cruz 12, 63, Roberts 45 | 3-1 | Wigan King 17(p) |
| 22/03/08 | Bolton | 0-0 | Man. City |
| 22/03/08 | Middlesbrough Sanli 32 | 1-0 | Derby |
| 22/03/08 | Newcastle Viduka 6, Owen 83 | 2-0 | Fulham |
| 22/03/08 | Reading Bikey 31, 79 | 2-1 | Birmingham Zarate 64 |
| 22/03/08 | Everton Yakubu 8 | 1-1 | West Ham Ashton 68 |
| 23/03/08 | Man. United Brown 34, Ronaldo 79, Nani 81 | 3-0 | Liverpool |
| 23/03/08 | Chelsea Drogba 73, 82 | 2-1 | Arsenal Sagna 59 |
| 29/03/08 | Birmingham Zarate 40, 54, McSheffrey 77(p) | 3-1 | Man. City Elano 59(p) |
| 29/03/08 | Bolton Taylor 14, 43 | 2-3 | Arsenal Gallas 62, Van Persie 68(p), Samuel 90(o) |
| 29/03/08 | Derby Villa 10, 80 | 2-2 | Fulham Kamara 24, Leacock 78(o) |
| 29/03/08 | Portsmouth Defoe 32, 90 | 2-0 | Wigan |
| 29/03/08 | Reading | 0-0 | Blackburn |
| 29/03/08 | Sunderland Jones 29, Reid 90 | 2-1 | West Ham Ljungberg 18 |
| 29/03/08 | Man. United Ronaldo 17, Tevez 33, Rooney 53, 70 | 4-0 | Aston Villa |
| 30/03/08 | Chelsea Carvalho 6 | 1-0 | Middlesbrough |
| 30/03/08 | Tottenham Bent 26 | 1-4 | Newcastle Butt 45, Geremi 52, Owen 65, Martins 83 |
| 30/03/08 | Liverpool Torres 7 | 1-0 | Everton |
